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Bears vs 49ers predictions, picks, odds

Chicago Bears at San Francisco 49ers odds, picks and predictions

The Chicago Bears (11-4) and San Francisco 49ers (11-4) meet for Sunday Night Football in Week 17 at Levi's Stadium in Santa Clara, California.

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Bears vs. 49ers predictions, picks, odds: Who wins Week 17 NFL game?

· 17h · on MSN

Bears vs. 49ers prediction, odds, start time: Week 17 'Sunday Night Football' picks from advanced model

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49ers vs. Bears best bets, picks and odds | Week 17 2025

The Chicago Bears (11-4) visit a streaking San Francisco 49ers (11-4) squad on Sunday, December 28, 2025 at Levi's Stadium (with best bets available).

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49ers vs. Bears 2025 Prediction, Odds, Picks - Dec 28

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Bears get concerning injury update for 49ers clash

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Five Bears, 49ers players to watch in NFL Week 17 game in San Francisco

The Bears’ linebacker made his return against the Green Bay Packers after missing four games with a groin injury.

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Micah's expectations for Bears vs 49ers in Week 17

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49ers won't have to face top Bears WR in Week 17 matchup

Around the NFL: Playoff positioning (and the No. 1 pick) up for grabs in Week 17

A trio of teams playing Sunday are vying to challenge Denver for the No. 1 seed in the AFC. New England is two-touchdown favorites over the New York Jets, Jacksonville is a 5.5-point road favorite at Indianapolis and Buffalo is a 1.

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49ers vs. Bears prediction, pick, odds for Sunday's NFL Week 17 game

A double-digit win is expected for the San Francisco 49ers (11-4) when they face the Chicago Bears (11-4) on Sunday, Dec. 28 at Levi's Stadium (starting at 8:20 p.m. ET). Our computer prediction has the final score as 30-18.