Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

The Noelin family of secreted proteins bind to the external portion of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane, a process necessary for transmission of ...

While the COVID pandemic has thankfully been over for some time now, there is still a considerable number of people in the world (about 400 million) suffering from long COVID. Long COVID is a chronic ...

Researchers headed by a team at Campbell Family Mental Health Research Institute Centre for Addiction and Mental Health (CAMH) reported promising data from preclinical in vivo studies evaluating a ...

The research, published June 4 in Nature Structural & Molecular Biology, identifies critical connections between activity of the epilepsy drug perampanel and the resulting movements of the AMPA ...