Caspases are a family of proteolytic enzymes that play a central role in apoptosis, the regulated process of programmed cell death essential for development, homeostasis and the clearance of damaged ...
Caspase Related Reagents Courtesy of Bingren Hu, Queen's Medical Center, Hawaii. Provided by Cell Signaling TechnologyConfocal micrograph of double immunostaining for cleaved caspase-3 (green) and ...
Scientists use cell death, whether by apoptosis or necrosis, to evaluate the toxicity or effectiveness of substances of interest, including potential therapeutic agents. For example, researchers will ...
Researchers at the Institut Pasteur and Inserm have developed a novel triple-therapy that reprograms how B cell cancers ...
Expression profiles associated with disease progression in non-small cell lung cancer. Background: Cisplatin is a platinum-based chemotherapeutic drug used for treating a variety of human cancers such ...
Cell death is a fundamental physiological process that all organisms undergo and is crucial for organ maintenance, autoimmunity, and embryonic development. Some of the different types of programmed ...
Minocycline is broadly protective in neurologic disease models featuring cell death and is being evaluated in clinical trials. We previously demonstrated that minocycline-mediated protection against ...
New research suggests that chronic stress disrupts the body’s natural mechanisms for repairing the intestinal lining by reducing levels of a specific regenerative protein. Scientists found that ...
Xevinapant or Placebo Plus Platinum-Based Chemoradiotherapy in Unresected Locally Advanced Squamous Cell Carcinoma of the Head and Neck (TrilynX): A Randomized, Phase III Study The following ...
Neurodegenerative disorders, such as Alzheimer's, Parkinson's, and Huntington's diseases, are characterized by progressive ...
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