Autophagy, a fundamental cellular process, involves the degradation and recycling of a cell's own components. This intricate mechanism begins with the ...

Image Caption: CRISPR-Cas9 library identified XPR1 as a potential gene regulating autophagy. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative ...

In hypoxia, the RNA molecule EUDAL keeps EGFR permanently active. This activates the STAT3/BNIP3 pathway, triggering ...

Mitochondria are central hubs for cellular stress adaptation, with their function integrated with both apoptosis and autophagy pathways that determine cell fate. Alterations in mitochondrial ...

Clinical trials pave the way for new cancer treatments. But they don't arise out of thin air. A new clinical trial for ovarian cancer patients at MUSC ...

Cancer Research UK-funded scientists have uncovered dementia-like behaviour in pancreas cells at risk of turning into cancer. The findings provide clues that could help in the treatment and prevention ...

Those affected slowly lose the strength they need for routine tasks and become vulnerable to dangerous falls and bone ...

Scientists at the University of Pennsylvania have shown for the first time that it’s possible to detect dormant cancer cells in breast cancer survivors and eliminate them with repurposed drugs, ...