Please provide your email address to receive an email when new articles are posted on . Aztreonam-avibactam was well tolerated and comparable in efficacy to meropenem. Pfizer plans to start the ...

Credit: Getty Images. The combination antibiotic consists of aztreonam, a monobactam β-lactam and avibactam, a broad-spectrum β-lactamase inhibitor. The investigational antibiotic combination ...

Avibactam does not inhibit Ambler class B enzymes (metallo-β-lactamases) and is not able to inhibit many of the class D enzymes. Pfizer holds the global rights to commercialize Zavicefta, with the ...

Avibactam is a first-in-class broad-spectrum β-lactamase inhibitor, which protects ceftazidime against degradation by Class A, C and some D, β-lactamases.Avibactam does not inhibit class B enzymes ...

The emergence of resistance to the combination of ceftazidime and avibactam in Klebsiella pneumoniae represents a critical challenge to modern antimicrobial therapy. Resistance arises primarily ...

EMBLAVEOTM is the first and only monobactam/β-lactamase inhibitor combination antibiotic therapy approved by the U.S. FDA to treat complicated intra-abdominal infections, including those caused by ...

Avibactam sodium and its free acid, avibactam, are diazabicyclooctane (DBO)–based, non-β-lactam β-lactamase inhibitors (BLIs) that are used to treat multi-drug–resistant Gram-negative bacterial ...

Akums Drugs & Pharmaceuticals, India’s largest contract development and manufacturing organization (CDMO), has announced the launch of aztreonam-avibactam injection, an advanced antibiotic therapy ...

Ceftazidime–avibactam is recommended, within its marketing authorisation, as an option for treating severe drug-resistant infections caused by gram-negative bacteria. This includes, but is not limited ...

Ceftazidime-avibactam combines a third-generation cephalosporin with a novel non-β-lactam β-lactamase inhibitor to target carbapenem-resistant Gram-negative pathogens. Avibactam restores ceftazidime ...

Ceftazidime–avibactam is a combination of ceftazidime, which is a third-generation cephalosporin, and avibactam, which is a next generation non-beta-lactam beta-lactamase inhibitor. Ceftazidime binds ...