In a recent study published in the journal Nature Communications, researchers present a method for constructing artificial viral vectors (AVVs) using the established structural components of ...

The unwinding and priming activities of the bacteriophage T4 primosome, which consists of a hexameric helicase (gp41) translocating 5′ to 3′ and an oligomeric primase (gp61) synthesizing primers 5′ to ...

The tail of bacteriophage T4 is shown before (left) and after (right) binding to a host cell. Upon attachment to the bacterium, the bacteriophage pierces the host cell envelope and injects its genomic ...

But many things can go wrong in this process. One main issue is that these gene therapy vehicles can travel to the wrong places and damage healthy cells. Now, scientists think that a type of virus ...

The study may provide clues to how similar viruses infect cells and suggest ways for developing a new class of antibiotics and other drugs to prevent illnesses caused by viral pathogens. Scientists at ...

WEST LAFAYETTE, Ind. – New findings in research led by Purdue University biologists provide further evidence that the protein envelope protecting DNA in viruses evolved billions of years ago from a ...

Venigalla B. Rao, PhD, has been studying bacteriophages for more than four decades, mostly in small laboratories with limited personnel and funding. But having a mere eight-person lab (four post-docs, ...

The alternative text for this image may have been generated using AI. Figure 3: The loose ternary structure of T4Dam–DNA–AdoHcy. The alternative text for this image may have been generated using AI.

Like microscopic machine shops, some viruses assemble their parts with the help of tiny motors. Now, researchers have figured out the structure and workings of the natural molecular motors in one ...

Aims: Novel anticancer strategies have employed bacteriophages as drug carriers and display platforms for anticancer agents; however, bacteriophage-based platforms maintain their natural antibacterial ...

were diluted in 0.85% NaCl and exposed to y irradiation (2.79 Gy/min) at room temperature (24*C). T4+ was more sensitive to inactivation than was P22, and the T4os mutant was even more sensitive than ...

Bacteriophages are a special type of virus that infect bacteria and have amazing structural and functional diversity. When a bacteriophage infects a bacterium, it can hijack the molecular machinery of ...