A new study suggests that the blood-brain barrier (BBB) remains intact in a widely used mouse model of Alzheimer’s disease.

Researchers have developed brain-on-a-chip technology that uses human tissue to model how the brain’s protective barrier ...

Merging biophysics with knowledge of how the brain handles waste led to an impressive 50 percent reduction of amyloid beta in mice brains and restoration of cognitive function.

A new nanomedicine targeting the blood–brain barrier clears amyloid-β by 45% and restores memory in Alzheimer’s models, ...

In lieu of animal experiments, researchers from the University of Rochester are using state-of-the-art microchips with human ...

There's a bouncer in everyone: The blood-brain barrier, a layer of cells between blood vessels and the rest of the brain, kicks out toxins, pathogens and other undesirables that can sabotage the brain ...

Focused ultrasound is just one strategy researchers are using to get drugs into the brain. This article first appeared in The Checkup, MIT Technology Review's weekly biotech newsletter. To receive it ...

The brain is a rather important organ, and as such, nature has gone to great lengths to protect it. The skull provides physical protection against knocks and bumps, but there’s a lesser-known defense ...

“If we want to address BBB dysfunction, we have to have a good human BBB model,” said Ziyuan Guo, a neurobiologist and stem cell scientist at Cincinnati Children's Hospital Medical Center. “The whole ...

Leakiness in the brain could explain the memory and concentration problems linked to long COVID. In patients with brain fog, MRI scans revealed signs of damaged blood vessels in their brains, ...