Sepsis, a critical condition characterized by life-threatening organ dysfunction, arises from a dysregulated host response to infection. The resultant immunosuppression constitutes the primary ...

Researchers at Brigham and Women's Hospital (BWH) have discovered a new cellular and molecular pathway that regulates CD4+ T cell response--a finding that may lead to new ways to treat diseases that ...

A panelist discusses how CD4 counts serve as measures of immune system status that typically increase by about 200 in the first year of antiretroviral therapy. Although there can be laboratory ...

Shared TCR signatures in IBD linked to HLA-DRB1 reveal common immune mechanisms across ulcerative colitis and Crohn’s disease ...

Idiopathic CD4 lymphocytopenia (ICL) is a clinical syndrome that is defined by CD4 lymphopenia of less than 300 cells per cubic millimeter in the absence of any primary or acquired cause of ...

CD4+ T cells, or helper T cells, are one type of lymphocyte that helps coordinate the immune response against infection and disease. They interact and activate other cells in the immune system. The ...

What Is the CD4:CD8 Ratio Test Used For? CD4 and CD8 are two types of white blood cells in your blood. White blood cells help your body fight infections. If you have HIV infection, your doctor may use ...