A new strategy developed by Professor Nathan Gianneschi grabs cancer-driving proteins and directs them to the cell’s disposal ...

Crystalline polymers assembled inside tumor cell lysosomes rupture membranes, release iron, and trigger immune-activating ...

Many patients with metastatic cancers receive therapy that is initially highly effective, often resulting in complete remission. However, cancer cells have a remarkable capacity to evolve resistance ...

The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it. However, the molecular mechanisms ...

Scientists have uncovered an unexpected reason why some cancers return after initially responding to treatment.

Thanks to modern therapies, a cancer diagnosis is no longer an automatic death sentence. But many patients still suffer from ...

Scientists discovered that certain cancer cells use a low-level activation of a DNA-dismantling enzyme—normally seen in cell death—to survive treatment. Instead of dying, these “persister cells” ...

Researchers in Japan have identified a striking new way immune cells strip DNA out of dying neighbors, a process they call ...

The National Cancer Institute has quietly moved a familiar and polarizing drug into its preclinical pipeline: ivermectin, long known as a popular dewormer for horses and a standard antiparasitic in ...

The bispecific ADC izalontamab brengitecan improved survival for patients with metastatic triple-negative breast cancer in a ...