High-risk MDS stem cells appear to have an unexpected “energy addiction,” relying far more heavily than healthy blood-forming cells on a molecule called NAD. Disrupting this energy pathway selectively ...

A compound found in turmeric stood out when scientists compared five natural substances in laboratory tests on cancer cells.

High-risk myelodysplastic syndrome, a bone marrow cancer that can turn into acute myeloid leukemia, is driven by stem cells that burn through an unusually large supply of one molecule: nicotinamide ...

A protein known as p53 is, of all tumor suppressors in human cancer, the most frequently altered by gene mutations. When ...

A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy. While aneuploidy is detrimental to regular cells, it occurs in as many as 90% of tumors. How ...

New research reveals that the secreted protein DKK1 helps oral squamous cell carcinoma resist cisplatin by keeping the SLC3A2 ...

The spread of cancer from a primary tumor to another place in the body, called metastasis, remains one of the greatest ...

A Johns Hopkins study shows chronic cigarette smoke exposure reprograms distinct lung stem cell populations through ...

Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung tissue, in ways that make them vulnerable to specific cancer-causing gene ...

Mount Sinai team finds that loss of p53 can also change how growth and tissue development signals are organized across a ...