This diagram illustrates how the combination of fibroblast growth factor 4 and ascorbic acid activates the JAK2–STAT3 signaling pathway, promoting the maturation of induced cardiomyocytes (iCMs). This ...

A protein-level tension sensor reveals how cell shape and sarcomere maturity determine where cardiomyocytes carry mechanical load.

Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) say that it is now possible for the first time to monitor the functional development and maturation of ...

Novel tissue-embedded nanosensor shows that co-culturing stem-cell-derived cardiomyocytes with endothelial cells leads to more functionally mature cardiomyocytes. Heart muscle cells, called ...