Most cases of autoimmune lymphoproliferative syndrome (ALPS) are associated with heterozygous mutations in the genes encoding CD95 (Fas receptor), CD95 ligand and the apoptotic enzyme caspase-10.
Cancerous tumours thrive by turning the body’s immune system against itself. By pretending to be damaged tissue, they trigger the body’s immune responses and then exploit the extra oxygen and ...
A parasite that may already be hiding in your brain has a shocking survival trick: it can infect the very immune cells sent to destroy it. Yet most people never get sick, and new research from UVA ...
Caspase-8 zwingt infizierte Immunzellen zum kontrollierten Zelltod und stoppt so die Vermehrung des Parasiten – ein entscheidender Schutzmechanismus im Gehirn.
Background. Paracoccidioides brasiliensis is equipped with an arsenal of virulence factors that are crucial for causing infection. Our group previously defined the NLRP3 inflammasome as a mediator of ...
The parasite that may already live in your brain can infect the very immune cells trying to destroy it, but new UVA Health research reveals how our bodies keep it under control. Small cell lung cancer ...
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