Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D ...

Gene regulation and chromatin dynamics constitute central themes in modern molecular biology, governing how the genetic blueprint is accessed and utilised during development, differentiation and ...

New work shows that physical folding of the genome to control genes located far away may have been an early evolutionary ...

The INO80 chromatin remodelling complex has various roles in genome maintenance, acting via nucleosome sliding and H2A.Z ...

This study is led by Professor Zhenhui Zhong (College of Life Sciences, Sichuan University, Chengdu, China). The authors investigated global chromatin states and gene expression levels in soybean. The ...

Understanding a drug’s mechanism of action (MOA) can greatly increase the likelihood of successful clinical trials by identifying biomarkers of patient response and providing a rationale for ...

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D ...

In an article published in the journal Nature Communications, scientists have studied a protein, called HP1, which is ...

Inside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are constantly wrapping and unwrapping DNA, and even minor missteps can lead to ...

DNA methylation is a widely studied epigenetic modification with crucial roles in gene regulation, development, and disease, particularly in cancer. It has immense potential as a biomarker for early ...