Homologous recombination is the process by which two chromosomes, paired up during prophase 1 of meiosis, exchange some distal portion of their DNA. Crossover occurs when two chromosomes, normally two ...

During meiosis, the "crossover" gene-swapping process provides the tension needed to properly divide chromosomes. In yeast, double-strand DNA breaks (the precursors to crossovers) have been shown to ...

Scientists at Fred Hutchinson Cancer Research Center have worked out the molecular underpinnings of how chromosomes make the right number of crossovers — important links that make it possible for ...

Chromosomes in egg cells within fetal ovaries must be spliced and sorted perfectly. A new landmark study from UC Davis shows how protecting Holliday junctions allows this to happen.

The biological research of UC Santa Cruz’s Needhi Bhalla to determine the molecular motions at the heart of heredity has yielded a new discovery: The proper transfer of genetic materials depends on ...

UC Davis researchers have confirmed a central idea about chromosome repair, more than a quarter century after it was first proposed. The finding is important to scientists who seek to understand DNA ...