The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...

A new method for visualising chromosomes is painting a truer picture of their shape, which is rarely like the X-shaped blob of DNA most of us are familiar with. Scientists at the BBSRC-funded Babraham ...

In a major leap forward for genetic and biomedical research, two scientists at the University of Missouri have developed a powerful new artificial intelligence tool that can predict the 3D shape of ...

During sexual reproduction, haploid gametes (i.e. eggs and sperm) are generated from diploid precursors through the specialized cell division of meiosis. Meiosis reduces ploidy by following one round ...

Holocentric chromosomes have evolved independently from X-shaped monocentric chromosomes multiple times in both animals and plants, but the mechanism behind the centromere-type transition is unknown.

Human fertility hinges on a delicate molecular ballet that begins even before birth. UC Davis researchers have uncovered how special protein networks safeguard chromosomes as eggs and sperm form, ...

Describe the basic principle of mitosis (why do cells undergo mitosis?). Diagram how an exact replica of the genetic material is made, including the numbers of chromosomes present at each phase of ...

Some chromosomes, such as B chromosomes, can increase their inheritance rate to their own advantage. These extra chromosomes are found in many plants, animals, and fungi and rely upon various ...

When a woman becomes pregnant, the outcome of that pregnancy depends on many things — including a crucial event that happened while she was still growing inside her own mother’s womb.

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Different kinds of chromosome segment inversions have been found in ...