A single psilocybin dose relieved chronic pain and depression-like symptoms in mice by rebalancing brain circuits that regulate mood and pain.

New research shows that psilocybin, the active compound in psychedelic mushrooms, can reduce both chronic pain and pain-related depression by modulating brain circuits rather than acting at the site ...

A new study reveals magic mushrooms' active compound, psilocybin, may ease chronic pain and depression. Experiments in mice ...

A new study reports that a single dose of psilocybin, quieted chronic pain and depression-like behavior within 24 hours.

Avoiding pain may provide short-term relief, but in the long term, it costs us. Emotional energy doesn’t just disappear. When ...

Penn researchers found that psilocybin can calm brain circuits tied to pain and mood, easing both physical suffering and ...

“Women are born with pain built in. It’s our physical destiny.” With those words, Kristin Scott Thomas’s character in the TV show Fleabag nailed a truth: that to be female is to be over-represented in ...

In experiments using mice that had long-term nerve or inflammation-related pain, the researchers gave a single dose of ...

Next Friday, October 10th is World Mental Health Day, and that’s why it's the perfect time to talk about the faith-brain ...

Penn Medicine researchers discovered that psilocybin can ease chronic pain and depression by subtly tuning serotonin activity ...

As we learn more about how pain processing can vary between women and men, it might lead to better treatments.