Malaria represents one of the most serious threats to human health worldwide, and preventing and curing this parasitic disease still depends predominantly on the administration of a small number of ...

Overall, Baum and colleagues have identified how this new class of antimalarials block the parasite reaching sexual maturity, and therefore, their spread from human to human via a mosquito bite. This ...

Four veterans who say they suffered a range of symptoms after taking an antimalarial drug while serving can proceed in suing ...

Aminopeptidases constitute a diverse family of enzymes responsible for cleaving N‐terminal amino acids from peptide substrates, a process central to protein turnover and nutrient acquisition in ...

LOS ANGELES — A federal judge threw out a lawsuit against the maker of an anti-malarial drug blamed for causing psychotic behavior and neurological damage to U.S. service members, ruling that the case ...

The antimalarial drug mefloquine could help treat genetic diseases such as cystic fibrosis, Duchenne muscular dystrophy, as well as some cancers. In these diseases, a mutation in the genetic code ...

This cartoon shows the newly identified mefloquine binding site causing the changes in the ribosome's dynamics which promote read-through of the premature stop codons. The main interactions are shown ...