A new non-addictive class of compounds developed by researchers at Purdue’s College of Pharmacy could lead to the treatment of chronic pain conditions, such as back pain and arthritis, in the absence ...

Clinical failure in the pharmaceutical industry remains at a staggering 90%. Failed drugs are costly, both financially and in terms of human suffering. The debate rages on about how best to fix the ...

Using artificial intelligence, researchers discovered a class of compounds that can kill methicillin-resistant Staphylococcus aureus (MRSA), a drug-resistant bacterium that causes more than 10,000 ...

An interdisciplinary team presents a new class of chemical compounds that can be reversibly oxidized and reduced. The compounds known as 'pyrazinacenes' are simple, stable compounds that consist of a ...

Antitumor activity and suppression of AKT pathway activation by PDK1 inhibitor SNS-391. This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This abstract does not include a full text ...

Antibiotic resistance is among the biggest global threats to human health. It was directly responsible for an estimated 1.27 million deaths in 2019 and contributed to nearly five million more. The ...