The relapsing–remitting (RR) mouse model uses transgenic SJL/J mice expressing, in a large proportion of their CD4 + T cells, a transgenic T-cell antigen receptor (TCR) recognizing MOG peptide 92–106 ...

Mucosal surfaces of mammals are exquisitely susceptible to colonization by pathogens and are populated by elaborate mucosal-associated lymphoid tissues that are rich in conventional and specialized ...

Mike Mathis wants to bring things together. His lifelong friends. The skills and experiences gleaned over his lifetime. The people of his community. This past weekend, that idea came to fruition, when ...

The microbiome has a profound influence on our health, but exactly how our resident bacteria wield their power is still unclear. A type of T cell appears to provide some answers for gastrointestinal ...

Modern life — through stress, diet, and environmental exposures — can lead to the loss of important gut bacteria, which may affect digestion, immunity, energy, and metabolism. Complete Commensal ...

Healthy humans harbor an enormous and diverse group of bacteria and other bugs that live within their intestines. These microbial partners provide beneficial aid in multiple ways -- from helping ...

Signals from the bacteria that harmlessly -- and often beneficially -- inhabit the human gastrointestinal tract boost the immune system's ability to kill a major respiratory pathogen, Klebsiella ...

Mucosal pathogens are responsible for many severe infectious diseases, including influenza, severe acute respiratory syndrome coronaviruses 1 and 2 (SARS-CoV-1 and SARS-CoV-2, respectively), ...

The gut’s natural inhabitants are key to preventing and fighting some infections. Take Clostridioides difficile, a bacterium causing severe diarrhea that can be life-threatening: it is more likely to ...