New work shows that physical folding of the genome to control genes located far away may have been an early evolutionary ...
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally ...
Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction. Until now, researchers believed that these so-called SMC motors that make ...
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally ...
The illustration shows DNA being folded into a loop by an SMC motor called cohesin (in purple/blue). The purple part of the motor (with a red/green label) is the protein subunit NIPBL, which acts as a ...
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