Researchers in China have determined to identify the genetic basis for the naked mole-rats’ increased longevity.
A study reveals the secrets behind the rodent’s remarkable ability to live 10 times longer than expected, without cancer or ...
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Evolutionary mutation in cGAS enhances naked mole-rat DNA repair
The secret to the naked mole-rats' extraordinarily long life may lie in subtle changes to just four amino acids, researchers ...
Blocking meiotic DNA replication in budding yeast prevents recombination initiation. This could indicate a direct coupling of the two processes, or the presence of a checkpoint system that detects ...
A recent study, undertaken by researchers at the Tokyo Metropolitan University and the Tokyo Metropolitan Institute of Medical Science (both Japan), unravels key steps in the process of homologous ...
Scientists have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair ...
BRCA gene expression is induced at the G1/S boundary in cultured cell lines (Gudas et al., 1996; Vaughn et al., 1996a,b) and primary tissues (Blackshear et al., 1998; Rajan et al., 1996), and the ...
Scientists at the Francis Crick Institute, in collaboration with Artios, have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer ...
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Boosting precision gene editing: Autophagy shifts DNA repair toward homologous recombination
Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...
"The DNA inside our cells is constantly experiencing damage, and DNA repair is happening all the time to fix that damage and ...
Distinguishing Renal Cell Carcinoma From Normal Kidney Tissue Using Mass Spectrometry Imaging Combined With Machine Learning Homologous recombination DNA repair deficiency (HRD) is a therapeutic ...
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