For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier, a compact layer of cells that protect the brain from ...

Getting drugs to the brain is difficult. The very thing designed to protect the brain's environment — the blood-brain barrier (BBB), tightly packed cells that prevent most substances from passing ...

Researchers led by Costas Arvanitis at Georgia Tech have developed a method using microbubbles and ultrasound to temporarily open the blood-brain barrier (BBB), enhancing drug delivery to the brain ...

Drug delivery to the brain remains challenging mainly due to the blood-brain barrier (BBB) that regulates the entrance of substances to the brain.We use a Nanotechnology approach to enhance drug ...

A new study suggests that the blood-brain barrier (BBB) remains intact in a widely used mouse model of Alzheimer’s disease.

Predictive model accelerates the development of nanoparticles as potential drug carriers for targeting neurodegenerative ...

Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature ...

The properties of the blood-brain barrier serve a vital protective role, but they also keep drugs from reaching the organ. Big pharmaceutical companies have been making deals for technologies that ...

While this protects the brain from external threats, it also presents a major challenge for treating neurological diseases, as many potentially therapeutic compounds are unable to cross. One potential ...

A mind-bending parasite may one day deliver drugs to the brain. Such proteins and the genes that produce them are often too big for viruses — the most common courier for gene therapy — to carry (SN: ...