DNA polymerase (pol) δ is essential for both leading and lagging strand DNA synthesis during chromosomal replication in eukaryotes. Pol δ has been implicated in the Okazaki fragment maturation process ...

This is a preview. Log in through your library . Abstract Strains of Escherichia coli with a mutation in the sof (dnaS) locus show a higher than normal frequency of recombination (are hyper rec) and ...

Focusing on the schematic illustration in a, two DNA polymerase molecules are active at the fork at any one time. One moves continuously to produce the new daughter DNA molecule on the leading strand, ...

Cells replicate half of their genome as short fragments that are put together later on. The way in which this process is linked to the formation of DNA–protein complexes called nucleosomes is now ...