ATP-binding cassette (ABC) transporters serve a variety of physiological functions as well as play key roles in drug resistance. The genome of the human malaria parasite, Plasmodium falciparum, ...

Malaria parasites multiply asexually in the human bloodstream, thereby causing chronic infection and all the complications associated with this devastating disease. During each round of multiplication ...

In the blood of its human host, a small number of asexually replicating Plasmodium falciparum parasites differentiate to initiate sexual development, i.e. gametocyte develop. Gametocyte development ...

Researchers at Weill Cornell recently published a study in Nature Microbiology that highlights the newly discovered intricacies of the malaria transmission cycle. The results of their study could have ...

Malaria is caused by a eukaryotic microbe of the Plasmodium genus, and is responsible for more deaths than all other parasitic diseases combined. In order to transmit from the human host to the ...

Scientists at Stockholm University and collaborators say they have used high-resolution genomic tools to map the global repertoire of genes of gametocyte development toward the male or the female ...

In hopes of fighting malaria by interfering with the life cycle of the malaria parasite, scientists have focused on a potential weak point—the part of the cycle in which the parasite, while in human ...

A key developmental step in the life cycle of the most virulent species of malaria parasite depends in part on a series of molecular signals, detailed in a new study led by researchers at Weill ...

A study has characterised the factors that cause the malaria parasite, Plasmodium falciparum, to invest resources into reproduction – to maximise transmission to other hosts – or replication – to ...

Gametocyte therapy involves making changes to gametes (egg and sperm cells) prior to conception..