Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten -- ...

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

On some level, biology is all about regulation, regulation, regulation. One way that our cells regulate their genes is through a process called alternative splicing, which entails the selective ...

Researchers have harnessed a bacterial immune defense system, known as CRISPR, to efficiently and precisely control the process of RNA splicing. The technology opens the door to new applications, ...

A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language. Darnell said the switch to the new NOVA1 variant likely occurred between ...

Putting the uniquely human version of a certain gene into mice changed the way that those animals vocalized to each other, suggesting that this gene may play a role in speech and language. Mice make a ...