Virion Therapeutics, LLC, a clinical-stage biotechnology company, developing novel T cell-based immunotherapies that utilize ...
Please provide your email address to receive an email when new articles are posted on . Among patients with low baseline HBsAg, 39% achieved HBsAg loss with tobevibart/elebsiran, which rose to 46% ...
Tune-401 achieved dose-dependent HBsAg reductions (mean 54% at 0.65 mg/kg) with durable, months-long pharmacodynamics after single dosing on stable nucleos(t)ide analog background. Multiple recipients ...
Combination tobevibart 300 mg + elebsiran 200 mg q4w achieved HDV RNA TND in 77% at week 72 and 88% at week 96, outperforming tobevibart monotherapy. Profound HBsAg lowering occurred with dual therapy ...
Please provide your email address to receive an email when new articles are posted on . Older age, male sex and increased hepatitis B surface antigen correlated with a higher risk for hepatic flare ...
Panel A shows the structure of HDV, which shares the hepatitis B surface antigen (HBsAg) envelope with hepatitis B virus. The virion contains a single-stranded, circular RNA genome of approximately ...
Patients with chronic hepatitis B virus (HBV) infection in the immune-tolerant phase may still experience hepatic inflammation and disease progression, and could benefit from early antiviral treatment ...