The cytochrome P450 enzymes constitute a diverse superfamily of haem-containing proteins that catalyse key oxidative reactions in steroid biosynthesis. In the steroidogenic pathway, these enzymes ...

Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...

This is a preview. Log in through your library . Abstract Cytochrome P450 (CYP) enzymes are responsible for the metabolism of numerous xenobiotics and endogenous compounds, including the metabolic ...

Sept. 16, 2003 — St. John's wort increases metabolism via the cytochrome P450 (CYP) enzyme system 3A4, according to the results of a study published in the Sept. 17 issue of The Journal of the ...

Possible interaction of 1 drug with more than 1 CYP isoform Unexpected drug-drug interactions in a patient carrying null alleles in 1 CYP isoform through inhibition of additional CYP isoforms.

In the broadest sense, immunomodulators are drugs that adjust immune responses, for example, modulation of cytokine levels. Cytokines are signaling proteins responsible for the regulation of immune ...

University of Massachusetts (UMass) Amherst food scientists have identified a set of metabolic enzymes that are upregulated in colon cancer-bearing mice and in human colon cancer cells, and could ...