Focused ultrasound combined with microbubbles is increasingly being used to safely and reversibly open the blood-brain barrier (BBB) for the treatment of brain tumors and neurodegenerative disorders.

The blood–brain barrier functions as an evolutionarily optimized vascular “filter,” permitting limited penetration of small molecules like temozolomide while effectively excluding most biologics from ...

A researcher at the University of Missouri has made a promising breakthrough in the quest to help people with amyotrophic ...

Focused ultrasound technology may allow medications to pass through the blood brain barrier to treat tumors in the brain ...

When mice exercise, their livers release GPLD1 into the bloodstream. The enzyme travels to the blood vessels surrounding the brain and removes TNAP from the surface of those cells. By trimming away ...

Scientists at MIMETAS have published a new study describing a scalable, self-assembling human blood-brain barrier (BBB) model that combines physiological relevance with high-throughput capability. The ...

For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier, a compact layer of cells that protect the brain from ...

While this protects the brain from external threats, it also presents a major challenge for treating neurological diseases, as many potentially therapeutic compounds are unable to cross. One potential ...

A team at the University of California, San Francisco has identified a specific liver-produced enzyme that explains, at the molecular level, how physical exercise protects the aging brain from ...

The blood-brain barrier protects the central nervous system by tightly regulating what crosses between the two compartments. Neurons are vulnerable if the barrier suffers damage or weakens with age, ...

Researchers develop synthetic markers that cross the blood-brain barrier, allowing for noninvasive monitoring of the living brain via blood tests.