Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...

The day when human sperm and eggs can be grown in the laboratory has inched a step closer, with the discovery of a way to recreate a crucial developmental step in a dish 1. “Epigenetic reprogramming ...

It may soon be possible to coax human skin cells into becoming functional eggs and sperm using a technique known as "in vitro gametogenesis." This involves the creation (genesis) of eggs and sperm ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Chromosomes in egg cells within fetal ovaries must be spliced and sorted perfectly. A new landmark study from UC Davis shows how protecting Holliday junctions allows this to happen.

Using liverwort (Marchantia polymorpha) as a model, researchers led by Prof. LI Hongju from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have explored the ...

In a proof-of-concept experiment, scientists demonstrated that you can create and fertilize human eggs in the lab using sperm ...

Julian Koplin receives research funding from Ferring Pharmaceuticals for an unrelated project. Neera Bhatia receives funding from UKRI Arts and Humanities Research Council for an unrelated project.