Hospitalized children who receive hypotonic maintenance intravenous (IV) fluids are at higher risk of developing hyponatremia than those receiving isotonic IV fluids, according to a recent ...

In general, 0.25% saline is rarely used as a hydration fluid by itself. Because of the tonicity gradient, free water would enter the red blood cells, causing them to swell. This could lead to cell ...

Hypotonic fluid administration has been the standard of care for maintenance fluid therapy in acutely ill children, but this approach is associated with hospital-acquired hyponatraemia and ...

Statement 1 Term neonates, children and young people receiving intravenous (IV) fluid therapy have their plasma electrolyte concentrations and blood glucose measured when starting IV fluids and then ...