EPFL scientists have now discovered that a DNA-sensing mechanism of the innate immune system - which is pivotal for the immediate defense against pathogens -- controls cellular senescence. The work is ...

When your body senses something is wrong—whether it's a damaged cell or a growing tumor—it can react in many ways. One of the most powerful is cellular senescence. This process stops a cell from ...

Scientists are closing in on a deceptively simple idea with radical implications: that a single protein signal in the blood can push aging immune cells to behave as if they were young again. Instead ...

Recently, we had the opportunity to speak with Robin Mansukhani, the founder and CEO of Deciduous Therapeutics, a San Francisco-based biotechnology company focused on restoring immune function to ...

T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...

Millions of people who recover from infections like COVID-19, influenza and glandular fever are affected by long-lasting symptoms. These include chronic fatigue, brain fog, exercise intolerance, ...

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation ...