The human genome encodes 45 kinesin motor proteins that drive cell division, cell motility, intracellular trafficking and ciliary function. Determining the cellular function of each kinesin would ...
Figure 1: Axonal transport of Bace, Ps1 and other kinesin-I cargoes is decreased in APP-null mutant mice. The decreased transport of kinesin-I and potential cargoes in APP-null sciatic nerves ...
For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...
Zachary Gergely, Ammon Crapo, Loren Hough, J. Richard McIntosh, and Meredith D. Betterton (2016). Molecular Biology of the Cell27, 3490. arXiv DOI: 1604.08134. DOI ...
Inside neurons, motor proteins haul precious cargo, moving essential goods along thread-like roadways called microtubule tracks. This miniature highway system is vital for keeping neurons healthy: ...
The structure of a key part of the machinery that allows cells to divide has been identified by researchers, opening new possibilities for throwing a wrench in the machine and blocking runaway cell ...
(PhysOrg.com) -- Life's smallest motor, a protein that shuttles cargo within cells and helps cells divide, does so by rocking up and down like a seesaw, according to research conducted by scientists ...
Biophysicists at Stanford University have finally answered one of the most fundamental questions in molecular biology: How does the tiny motor molecule, known as kinesin, move across a living cell?
One of the hallmarks of cancer is the uncontrolled growth of cells that leads to tumours forming. Using chemotherapy that disrupts the machinery needed for cell division is commonly used to tackle ...
The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis — opening new possibilities for throwing a wrench in ...
Life's smallest motor, a protein that shuttles cargo within cells and helps cells divide, does so by rocking up and down like a seesaw, according to research conducted by scientists at the U.S.
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