Bacterial lipoproteins are essential components of the cell envelope, serving diverse roles that range from maintaining membrane integrity to mediating virulence and antibiotic resistance. These ...
Researchers develop enterololin, a new antibiotic that selectively targets harmful gut bacteria, aided by AI model DiffDock.
Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, No. 3 (1990), pp. 909-913 (5 pages) Lipoprotein lipase (LPL) catalyzes the flux-generating step in transport ...
A study published in Nature of the LolCDE complex, as detailed through various experimental approaches and analyses, provides a comprehensive understanding of its structure, function, dynamics, and ...
Lipoprotein(a) is a presumed risk factor for atherosclerotic cardiovascular disease. Olpasiran is a small interfering RNA that reduces lipoprotein(a) synthesis in the liver. We conducted a randomized, ...
A new nanomedicine targeting the blood–brain barrier clears amyloid-β by 45% and restores memory in Alzheimer’s models, ...
Lipoprotein apheresis involves the extracorporeal removal of LDL and lipoprotein(a) particles from whole blood or plasma by adsorption, precipitation or differential filtration. Used repetitively, ...
High levels of good cholesterol (high density lipoprotein (HDL)) are associated with protection from cardiovascular disease, which remains the leading cause of death in the United States. But what ...
Lipoprotein(a) levels are genetically determined and, when elevated, are a risk factor for cardiovascular disease and aortic stenosis. There are no approved pharmacologic therapies to lower ...
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