Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

The liver stands as a powerhouse organ, orchestrating a symphony of crucial functions essential for our overall health. It serves as the body’s primary detoxifier, meticulously removing harmful ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

Many biological processes exhibit daytime differences governed by rhythmic exposure to sunlight, termed circadian rhythms. Researchers at Penn State recently found, in mice, that a protein critical to ...

Shift work and irregular eating patterns could affect liver function and disrupt its delicate circadian rhythm, University of ...

The liver, located in the upper right side of the abdomen, is the body’s largest organ and one of the most important. The liver performs hundreds of vital functions, including converting nutrients ...

Non-alcoholic fatty liver disease affects millions of Americans, often silently. The good news? Research shows that a few everyday foods can make a real difference in liver fat, glucose control, and ...

Trish Lalor does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...

Discover how a miniature model of the human liver can help improve toxicology testing for food contaminants, reducing the ...