CADASIL, an inherited disease caused by mutations in the NOTCH3 gene, damages the brain’s small blood vessels, leading to ...

The immune system depends on molecular alarms that detect danger inside cells. One of these alarms is STING, short for ...

Researchers have found that a genetic mutation associated with a rare group of blood cancers does not always result in ...

Biology has clever ways to mask the effects of potentially harmful gene mutations. Scientists are investigating how this ...

DNA has to be interpreted by cells. The letters or bases that make up genetic sequences are read in sets of three, and those three-base sequences are known as codons. Every codon encodes for one amino ...

Some house mice throughout New York, New Jersey, Pennsylvania and Washington, D.C., carry genetic mutations that render ...

A team of researchers led by Professor Akitsu Hotta (Department of Clinical Application) developed a comprehensive framework ...

Researchers recently identified 12 genetic variants linked to longer lives, potentially paving the way for anti-aging ...

Autism spectrum disorder is complex; it presents differently in different patients, and the causes are still unclear, even though hundreds of small changes in gene sequences have been linked to an ...

C-to-T transitions in CpG dinucleotides are the most prevalent mutations in human cancers and genetic diseases. These mutations have been attributed to deamination of 5-methylcytosine (5mC), an ...

Genetic disorders—like cystic fibrosis and Huntington's disease—are considered incurable, with gene mutations occurring in essentially every cell of the body. Gene mutations occur when one nucleotide ...

Shocking mutations in the DNA of common pests found in every major US city could help spark the next deadly pandemic, ...