In juvenile myoclonic epilepsy, data are limited on the genetic basis of networks promoting convulsions with diffuse polyspikes on electroencephalography (EEG) and the subtle microscopic brain ...

A new study shows that wearable sensor technology can be used to reliably assess the occurrence of myoclonic jerks in patients with epilepsy also in the home environment. A new study by the University ...

A recent report has described the use of video-electroencephalography (video-EEG) in the management of patients with atypical juvenile myoclonic epilepsy (JME). The work highlights the importance of ...

A 20-year-old woman presented to a specialist epilepsy center with seizures, myoclonus, ataxia, and impaired executive functions. She was born to unrelated parents, had febrile seizures in infancy, ...

Loss-of-function mutations in the gene (CSTB) encoding human cystatin B, a widely expressed cysteine protease inhibitor, are responsible for a severe neurological disorder known as Unverricht-Lundborg ...

STEVENAGE, England--(BUSINESS WIRE)--Autifony Therapeutics Limited (“Autifony”), which is pioneering the development of novel pharmaceutical treatments for rare CNS disorders and other serious brain ...

Provoked seizures are not considered to be epilepsy, which is defined as two or more unprovoked seizures, and provoked seizures typically do not require long-term treatment with antiseizure medication ...

Levetiracetam reduces tonic-clonic seizures by over 77% in clinical studies. Ethosuximide is highly effective for absence seizures, especially in children. Valproate remains the gold standard for ...

GREENWICH — When Patrick Clisham was a freshman at Greenwich High School, his first seizure came on without warning, shocking him and his family. His parents hoped it was a “one-and-done” event, but ...

This report illustrates in detail the typical course of LD, from its earliest phases through its progression to eventual death. It is important for clinicians to distinguish LD from the much more ...