Chronic Granulomatous Disease (CGD) is a rare, inherited immunodeficiency caused by mutations in one or more components of the NADPH oxidase complex. This defect compromises the ability of phagocytes ...
Chronic granulomatous disease (CGD) describes an inherited genetic condition that affects a person’s immune system. It results in a type of immunodeficiency and causes people to be highly susceptible ...
In the center, a mouse model of both colitis and periodontitis is depicted on the left, showing the extensive periodontal tissue damage caused by inflammation. On the right, a cluster of macrophages ...
This new article publication from Acta Pharmaceutica Sinica B, discusses how diabetes-associated sleep fragmentation impairs liver and heart function via SIRT1-dependent epigenetic modulation of NADPH ...
Xiao Wen Mao, Nina C. Nishiyama, Mary Campbell-Beachler, Peter Gifford, Kristine E. Haynes, Daila S. Gridley and Michael J. Pecaut The purpose of this study was to determine whether nicotinamide ...