Jaguars vs Colts predictions, picks, odds. Who wins Week 17 NFL game?

The Jacksonville Jaguars play the Indianapolis Colts in Week 17 of the 2025 NFL season. Who wins? See our predictions and picks, plus game odds.

Florida NFL wrapup for Dec. 29: Dolphins knock off Bucs, Jaguars win

Despite a loss to the Dolphins, the Bucs can still win the NFC South by defeating Carolina in Week 18; the Jaguars take care of business vs. Colts.

What a Win (and Loss) Means for Jaguars vs. Colts

The Jacksonville Jaguars travel to the Midwest to face the Indianapolis Colts in a critical AFC South bout that could either clinch the division for the Jaguars

NFL releases Week 18 schedule with playoff berths on the line

The final slate of games for the 2025 NFL regular season is set.

NFL playoff picture: Eagles scenarios following Bills win; two divisions will be decided next week

The Eagles are one of four teams in the NFL that have clinched their division, but could still move up in the playoff standings thanks to their 13-12 win against the Buffalo Bills Sunday. Unfortunately,

Colts lose to Jaguars 23-17, drop to 8-8

Indianapolis Colts cornerback Kenny Moore II discusses the team's 23-17 loss to the Jacksonville Jaguars. Clark Wade. Watch Next

NFL Week 18 Schedule and Times for All Games Set, Who Got Flexed to Saturday & SNF?

The Week 18 schedule is set. With just one game remaining in the 2025 NFL regular season and plenty of playoff seeding still up for grabs, the NFL schedule-makers flexed some doozies for the Saturday games and Sunday Night Football.

Jacksonville Jaguars squeak past Colts, 23-17, to hold AFC South lead

The Jacksonville Jaguars improved to 12-4 after defeating the Indianapolis Colts 23-17 on the road. Next up for Jax? A shot at the AFC South title.
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