Mitochondrial dysfunction characterizes a range of neurodegenerative disorders, including Alzheimer's, Parkinson's, and Huntington's diseases, ALS, and multiple sclerosis. In such conditions, abnormal ...

Despite being renowned as the “powerhouse of the cell,” mitochondria can also be a source of heartache for those living with mitochondrial disease—especially when planning to have children. Because ...

Mitochondria possess their own DNA (mtDNA), which plays important roles in cellular respiration and energy consumption.

Researchers found that altered B cell function in children with mitochondrial disorders led to a weaker and less diverse antibody response to viral infections. Researchers analyzed gene activity of ...

In a major step toward treating rare mitochondrial diseases, researchers in the Netherlands have successfully corrected harmful mutations in mitochondrial DNA using a precision gene-editing tool.

Children born to women who carry pathogenic variants in mitochondrial DNA (mtDNA) are at risk for a range of clinical syndromes collectively known as mtDNA disease. Mitochondrial donation by ...