The cytotoxic (killing) function of T cells is central to their activity in immune defence — for example in eliminating infected or cancerous cells — but it was not until 1970 that cytotoxic activity ...

As a part of our immune defenses, cytotoxic T cells – or killer T cells – seek out and destroy cells that are infected or cancerous. This process is essential for the body's defense against diseases.

The scientists made the discovery by studying perforin, which is the protein responsible for the hole-punching. They found that perforin's attachment to the cell surface strongly depends on the order ...

Cancer cells are adept at escaping death. One of the ways in which cancer cells prevent death from fatal attacks by cytotoxic T lymphocytes (CTLs) is by efficiently repairing damage to their cell ...

Peter Mac scientists are part of a research team that has determined the structure of a pore-forming protein used by the immune system to kill unwanted cells. The work was led by researchers in the ...

As a part of our immune defences, cytotoxic T cells – or killer T cells – seek out and destroy cells that are infected or cancerous. This process is essential for the body’s defence against diseases.

Research led by the University of Sydney, Australia, has uncovered an important driver of critical SARS-CoV-2 infections. In their paper, "A unique cytotoxic CD4+ T cell-signature defines critical ...