Telomere length and polygenic risk scores (PRS) are linked to idiopathic pulmonary fibrosis (IPF) risk, especially in noncarriers of rare genetic variants. The study identified rare damaging variants ...

Over a century after Mendel established the foundations of inheritance, genomics has revealed that most human traits and common diseases arise from the ...

Cardiovascular disease ("CVD") is the leading cause of death in the US and worldwide with over 82 million Americans living with CVD. CVD accounts for one in every three deaths in the US, or more than ...

Large genetic study links telomere-related polygenic risk to distinct idiopathic pulmonary fibrosis subgroups, improving disease prediction.

Despite major advances in genetic testing for breast cancer risk prediction, death rates remain disproportionately high among ...

Combining a polygenic risk score (PRS) with traditional biomarkers can help clinicians better estimate a patient’s risk of developing coronary artery disease (CAD), according to new UK Biobank data.

A polygenic risk score (PRS) may help identify women who are at a greater risk of developing a future breast cancer after treatment for in situ breast disease, a retrospective study suggests. The ...

Cancer is challenging to treat, yet identifying individuals with greater risk of developing disease can assist with early detection and increased treatment efficacy. There are several types of risk ...

The addition of polygenic risk scores (PRS) improved the accuracy of the cardiovascular disease (CVD) risk prediction tool PREVENT across all groups studied, across ancestries. Over 3 million people ...