Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby regulate proteins. Malfunctioning of DUBs could lead to diseases, including ...

Peroxiredoxins are among the most abundant enzymes involved in managing oxidative stress. They control the levels of peroxides such as hydrogen peroxide, relay redox signals, and help protect other ...

Scientists have developed a novel approach to modifying enzymes to improve functionality. They designed a new algorithm to make multiple changes to an enzyme sequence at once as compared to the ...

Enzymes are proteins that guide (catalyze) very specific chemical reactions. They play indispensable roles in all life forms. Some enzymes carry out the day-to-day business of biology like digesting ...

Researchers synthesize enzymes to learn more about a signaling protein involved in the development of muscle, bone and blood in vertebrate embryos. A team of bioengineers at the University of Texas at ...

Healthy cells are constantly breaking down proteins and building up new ones with the help of enzymes aptly named unfoldases, because they unravel proteins tagged for destruction or recycling. Now, a ...

In nature, evolution takes years to sculpt new traits. In the lab, scientists hope to achieve this feat much faster: Being able to evolve proteins with enhanced or novel functions has important ...

Hidden in volcanic lakes and deep-sea vents, scientists have discovered tough new DNA-binding proteins built to survive extreme conditions. After scanning huge genetic databases, researchers found ...

Connecticut-based company partners with laboratories to explore how enzymes can break down plastic and textile scrap to make new resins. Protein Evolution says its technique can create rPET resin “is ...

Coronaviruses not only use the machinery of the human cells they infect: they modify them to achieve optimal conditions to ...

A research team led by Sahand Jamal Rahi at EPFL’s Laboratory of the Physics of Biological Systems has introduced a new ...