Take a look at the mechanism and the variables behind decarboxylation, to make sure you get higher the next time you make edibles. THC, and all cannabinoids, starts out with an acid group that ...

Oxidative decarboxylation of pyruvate to form acetyl–coenzyme A, a crucial step in many metabolic pathways, is carried out in most aerobic organisms by the multienzyme complex pyruvate dehydrogenase.

Figure 2: Stereo view of the active site of pyruvate oxidase F479W with the two neighboring cofactors ThDP and FAD and the amino acid residues in close proximity to the reactive C2 carbon atom of ThDP ...

Bethany Halford Bethany Halford is a Senior Correspondent for C&EN based in Boston. Once upon a time Bethany was a synthetic organic chemist, churning out new molecules. She used to tell people she ...

Pyruvate is produced by glycolysis, a process in which carbohydrates are broken down to create energy. Calcium pyruvate is a popular supplement that many people use primarily for its purported weight ...

Acetolactate synthase, also known as acetohydroxyacid synthase (AHAS), is an enzyme involved in the branched chain amino acid biosynthesis pathway. AHAS is a thiamine diphosphate (ThDP)-dependent ...

During glycollate oxidation, glyoxylate was decarboxylated by pea leaf protoplasts. The characteristics of the reaction were similar to those of the reaction in leaf extracts (Walton, 1982, Planta 155 ...

Indications: Pyruvate dehydrogenase complex deficiency, typically associated with post-prandial lactic acidemia with a normal lactate/pyruvate ratio, can be assayed in freshly isolated blood ...