Figure 1: The RAG2 PHD finger is a novel H3K4me3-binding module. Figure 2: The molecular basis of H3K4me3-recognition by RAG2 PHD. Figure 4: Recognition of H3K4me3 is crucial for RAG1/2 recombinase ...
The generation of lymphocyte-specific antigen receptors by V(D)J recombination is controlled by levels of recombination-activating gene 2 (RAG2) protein, which accumulates during the G1 (gap 1) phase ...
The “R2G2” (B6;129-Rag2tm1FwaIL2rgtm1Rsky/DwlHsd) knockout mouse is the latest advancement to provide an alternative option in the highly immunodeficient mouse model category for oncology, immunology ...
In a recent study published in Nature Communications, researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications. Study: CRISPR-Cas9 ...
Scientists have long sought ways to sic the body's own immune system on cancer cells. But such immunotherapies, while elegant in theory, have proved elusive in practice. Part of the difficulty has ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results