The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...
The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and a process fundamental to all life. But the inner workings of this ...
Water molecules play an active, essential role in gene transcription, helping RNA polymerase II carry out the chemical steps needed to read DNA and build RNA. Researchers have uncovered a previously ...