Design-Reuse

Rad3 Communications announces the acquisition of Raithlin Semiconductor's LDPC IP Cores and development team

Calgary, Canada – May 11, 2009 – RAD3 Communications Inc. (RAD3), a communications intellectual property (IP) company, today announced the acquisition of the LDPC IP assets of Raithlin ...
Design-Reuse

Rad3 Communications Inc. announces the appointment of Dr. Stephen Bates to the position of Chief Architect

Calgary, Canada – April 18th , 2010 – RAD3 Communications Inc. (RAD3), a communications intellectual property (IP) company, is pleased to announce that Dr. Stephen Bates has joined the company as ...
JSTOR Daily

Serine-345 is Required for Rad3-Dependent Phosphorylation and Function of Checkpoint Kinase Chk1 in Fission Yeast

Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, No. 20 (Sep. 25, 2001), pp. 11289-11294 (6 pages) Genome integrity is monitored by a checkpoint that delays ...
Nature

Rad3-dependent phosphorylation of the checkpoint clamp regulates repair-pathway choice

When replication forks collapse, Rad3 phosphorylates the checkpoint-clamp protein Rad9 in a manner that depends on Thr 225, a residue within the PCNA-like domain. The physiological function of Thr 225 ...
ascopubs.org

Ataxia Telangiectasia–Mutated and Rad3-Related Inhibition and Topoisomerase I Trapping Create a Synthetic Lethality in Cancer Cells

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated. Relationships are self-held unless noted. I = Immediate Family ...
Science Daily

Structural knowledge of the DNA repair complex

New research provides mechanistic insight into how DNA is monitored and repaired if damage occurs. The results may eventually help to improve the treatment of certain types of cancer, as the DNA ...