Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely ...

A new mechanism for the deactivation of switch proteins has been identified. Switch proteins such as Ras regulate many processes in the body and affect diseases such as cancer. A new mechanism for the ...

Switch proteins such as Ras regulate many processes in the body and affect diseases such as cancer. The research team published their report on the newly discovered mechanism in the current issue of ...

Researchers from Bochum and Osnabrück have gained new insights into the structure of the Ras protein, which acts as a molecular switch for cell growth and is involved in the development of cancer.

In accordance with the features of RAS protein function essential for RAS-dependent cancer growth (membrane association, GTP binding, effector signaling), a variety of logical directions have been ...

A cancer-causing protein long thought to be resistant to medication could soon be the target of new drugs, thanks to the work of Quebec researchers who used synchrotron light to find and exploit its ...

A cancer-causing protein long thought to be resistant to medication could soon be the target of new drugs, thanks to the work of Quebec researchers who used synchrotron light to find and exploit its ...

Bochum biophysicists in collaboration with the MPI Dortmund have for the first time measured the orientation of the Ras protein bound to the cell membrane. The RUB team combined the use of three ...

Find a tumor in a human or rodent, and the chances are that lurking within it will be an activated ras gene. The cancer-police have been trailing it for the better part of two decades and the file of ...

The Journal of Cell Biology (JCB) is a not-for-profit publication, edited by scientists, and a leading life sciences journal. The JCB publishes papers on all aspects of cellular structure and function ...