Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Tumor-wide RNA splicing aberrations and their potential as therapeutic neoantigen targets. Phase 1/2, open-label, first-in-human study of the anti-GPC3 T-cell engager SAR444200 in patients with ...

Cervical squamous cell carcinoma (CESC), the most prevalent subtype of cervical cancer, remains a major global health burden driven primarily by persistent high-risk HPV infection and genetic ...

Out of touch: Understanding the frequency and trajectory of chemotherapy-induced neuropathy peripheral (CIPN) in breast cancer survivors. Incidence of ocular toxicities in patients with ...

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...

Leveraging single-cell sequencing, this study presents the first cell-resolved molecular map of human scalp aging, revealing that the core mechanism of early senescence involves a significant ...

Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning ...

10x Genomics is stepping up to buy Scale Biosciences and its single-cell profiling solutions, with plans to implement them within the company’s Chromium platform. The deal for the recent Fierce ...

Background RNA 5-methylcytosine (m5C) has emerged as a critical epigenetic regulator in cancer biology, yet its role in the tumour immune microenvironment (TME) remains incompletely understood.