Plasticity among cell lineages is a fundamental, but poorly understood, property of regenerative tissues. In the gut tube, the small intestine absorbs nutrients, whereas the colon absorbs electrolytes ...

Trends of colorectal cancer-related mortality among patients with comorbid type 2 diabetes in the United States, 1999–2020. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...

A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide and renew ...

Colonoscopy is a common procedure that’s used to diagnose and monitor conditions affecting your colon and rectum. It can be used to detect conditions like colorectal cancers and precancers, IBD, and ...

The gut microbiome is an important ecosystem of microbes that lives in each one of us, and its strength affects our overall health. However, the small intestine is an underappreciated part of the gut ...

This story is part of a series exploring human anatomy and physiology complexities. Each story in this collection showcases discoveries reshaping our understanding of the body's inner workings, ...

Paneth cell metaplasia (PCM), long viewed as a consequence of chronic inflammation in ulcerative colitis, may also help ...