Lipid-based drug delivery is increasingly being used to tackle oral bioavailability challenges resulting from poor solubility. Lipid-based drug delivery is increasingly being used to tackle oral ...
SEDDS and SMEDDS improve solubility and permeability while expanding efficacy and applicability. With the majority of APIs under development considered poorly soluble and/or poorly permeable, ...
Cardiovascular disease is among the major causes of morbidity and mortality in industrialized countries (1). Although cardiovascular disease affects almost exclusively adults, atherosclerosis, which ...
Over 141,000 bottles of cholesterol medication have been recalled due to “failed dissolution specifications,” suggesting that the drugs did not pass a solubility test, or failed to dissolve at a ...